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Structural Models for Interactions between the 20S Proteasome and Its PAN/19S Activators

Proteasome activity is regulated by sequestration of its proteolytic centers in a barrel-shaped structure that limits substrate access. Substrates enter the proteasome by means of activator complexes that bind to the end rings of proteasome α subunits and induce opening of an axial entrance/exit por...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Stadtmueller, Beth M., Ferrell, Katherine, Whitby, Frank G., Heroux, Annie, Robinson, Howard, Myszka, David G., Hill, Christopher P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804157/
https://ncbi.nlm.nih.gov/pubmed/19889631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C109.070425
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