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The pore of activated 20S proteasomes has an ordered 7-fold symmetric conformation

The 20S proteasome is a large multisubunit assembly that performs most of the intracellular non-lysosomal proteolysis of eukaryotes. Substrates access the proteasome active sites, which are sequestered in the interior of the barrel-shaped structure, through pores that are opened by binding of activa...

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Detalhes bibliográficos
Main Authors: Förster, Andreas, Whitby, Frank G., Hill, Christopher P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC202378/
https://ncbi.nlm.nih.gov/pubmed/12941688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg436
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