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The pore of activated 20S proteasomes has an ordered 7-fold symmetric conformation
The 20S proteasome is a large multisubunit assembly that performs most of the intracellular non-lysosomal proteolysis of eukaryotes. Substrates access the proteasome active sites, which are sequestered in the interior of the barrel-shaped structure, through pores that are opened by binding of activa...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Oxford University Press
2003
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC202378/ https://ncbi.nlm.nih.gov/pubmed/12941688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg436 |
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