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Structural Models for Interactions between the 20S Proteasome and Its PAN/19S Activators
Proteasome activity is regulated by sequestration of its proteolytic centers in a barrel-shaped structure that limits substrate access. Substrates enter the proteasome by means of activator complexes that bind to the end rings of proteasome α subunits and induce opening of an axial entrance/exit por...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2804157/ https://ncbi.nlm.nih.gov/pubmed/19889631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C109.070425 |
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