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Proteomic Analysis of GLUT4 Storage Vesicles Reveals LRP1 to Be an Important Vesicle Component and Target of Insulin Signaling

Insulin stimulates the translocation of intracellular GLUT4 to the plasma membrane where it functions in adipose and muscle tissue to clear glucose from circulation. The pathway and regulation of GLUT4 trafficking are complicated and incompletely understood and are likely to be contingent upon the v...

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Autori principali: Jedrychowski, Mark P., Gartner, Carlos A., Gygi, Steven P., Zhou, Li, Herz, Joachim, Kandror, Konstantin V., Pilch, Paul F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804154/
https://ncbi.nlm.nih.gov/pubmed/19864425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.040428
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