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Insulin-responsive amino peptidase follows the Glut4 pathway but is dispensable for the formation and translocation of insulin-responsive vesicles

In fat and skeletal muscle cells, insulin-responsive amino peptidase (IRAP) along with glucose transporter 4 (Glut4) and sortilin, represents a major component protein of the insulin-responsive vesicles (IRVs). Here, we show that IRAP, similar to Glut4 and sortilin, is retrieved from endosomes to th...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Pan, Xiang, Meriin, Anatoli, Huang, Guanrong, Kandror, Konstantin V.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724691/
https://ncbi.nlm.nih.gov/pubmed/30943117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-12-0792
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