Proteomic Analysis of GLUT4 Storage Vesicles Reveals LRP1 to Be an Important Vesicle Component and Target of Insulin Signaling

Insulin stimulates the translocation of intracellular GLUT4 to the plasma membrane where it functions in adipose and muscle tissue to clear glucose from circulation. The pathway and regulation of GLUT4 trafficking are complicated and incompletely understood and are likely to be contingent upon the v...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jedrychowski, Mark P., Gartner, Carlos A., Gygi, Steven P., Zhou, Li, Herz, Joachim, Kandror, Konstantin V., Pilch, Paul F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2010
Gaiak:
Membrane Transport, Structure, Function, and Biogenesis
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804154/
https://ncbi.nlm.nih.gov/pubmed/19864425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.040428
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