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The p85β regulatory subunit of phosphoinositide 3-kinase has unique and redundant functions in B cells

Phosphoinositide kinase (PI3K) is activated by various receptors on lymphocytes and regulates development, activation, and tolerance. Genetic ablation of PI3K function in T cells leads to the appearance of autoimmune disorders. In B cells, loss of the class IA regulatory subunit p85α causes a partia...

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Detalhes bibliográficos
Main Authors: OAK, JEAN S., CHEN, JING, PERALTA, RAECHEL Q., DEANE, JONATHAN A., FRUMAN, DAVID A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804088/
https://ncbi.nlm.nih.gov/pubmed/19811262
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