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Targeted therapy for the loss of von hippel-lindau in renal cell carcinoma: A novel molecule that induces autophagic cell death

Radiation and conventional cytotoxic chemotherapies are ineffective in treating renal cancer. Approximately 75 percent of renal cell carcinoma (RCC) is associated with an inactivation of the tumor suppressor gene von Hippel-Lindau (VHL). We exploited the possibility of targeting VHL-deficient RCC th...

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Bibliografische gegevens
Hoofdauteurs: Turcotte, Sandra, Sutphin, Patrick D., Giaccia, Amato J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803726/
https://ncbi.nlm.nih.gov/pubmed/18769110
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