Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau.
Screening of cDNA libraries prepared from the frontal cortex of an Alzheimer disease patient and from fetal human brain has led to isolation of the cDNA for a core protein of the paired helical filament of Alzheimer disease. The partial amino acid sequence of this core protein was used to design syn...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1988
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280359/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3131773/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.11.4051 |
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