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Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau.

Screening of cDNA libraries prepared from the frontal cortex of an Alzheimer disease patient and from fetal human brain has led to isolation of the cDNA for a core protein of the paired helical filament of Alzheimer disease. The partial amino acid sequence of this core protein was used to design syn...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Goedert, M, Wischik, C M, Crowther, R A, Walker, J E, Klug, A
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1988
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280359/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3131773/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.11.4051
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