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Glucose stimulates proinsulin biosynthesis by a dose-dependent recruitment of pancreatic beta cells.

Glucose is a well-known stimulus of proinsulin biosynthesis. In purified beta cells, the sugar induces a 25-fold increase in the synthesis of insulin immunoreactive material over 60-min incubation. Autoradiographic analysis of the individual cells shows that this effect is achieved via dose-dependen...

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Autori principali: Schuit, F C, In't Veld, P A, Pipeleers, D G
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1988
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC280320/
https://ncbi.nlm.nih.gov/pubmed/3287379
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