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Glucose stimulates proinsulin biosynthesis by a dose-dependent recruitment of pancreatic beta cells.

Glucose is a well-known stimulus of proinsulin biosynthesis. In purified beta cells, the sugar induces a 25-fold increase in the synthesis of insulin immunoreactive material over 60-min incubation. Autoradiographic analysis of the individual cells shows that this effect is achieved via dose-dependen...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Schuit, F C, In't Veld, P A, Pipeleers, D G
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1988
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280320/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3287379/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.11.3865
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