Regulated expression of genes inserted at the human chromosomal beta-globin locus by homologous recombination.

We have examined the effect of the site of integration on the expression of cloned genes introduced into cultured erythroid cells. Smithies et al. [Smithies, O., Gregg, R.G., Boggs, S.S., Koralewski, M.A. & Kucherlapati, R.S. (1985) Nature (London) 317, 230-234] reported the targeted integration of...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Nandi, A K, Roginski, R S, Gregg, R G, Smithies, O, Skoultchi, A I
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1988
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280316/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3375244/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.11.3845
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