Regulated expression of genes inserted at the human chromosomal beta-globin locus by homologous recombination.
We have examined the effect of the site of integration on the expression of cloned genes introduced into cultured erythroid cells. Smithies et al. [Smithies, O., Gregg, R.G., Boggs, S.S., Koralewski, M.A. & Kucherlapati, R.S. (1985) Nature (London) 317, 230-234] reported the targeted integration of...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1988
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280316/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3375244/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.11.3845 |
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