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Dopamine D1 receptor (DRD1) genetic polymorphism: pleiotropic effects on heritable renal traits

Because dopamine D(1) receptors (DRD1) influence renal sodium transport and vascular hemodynamics, we examined whether genetic polymorphisms play a role in renal function. We conducted polymorphism discovery across the DRD1 open reading frame and its 5′-UTR and then performed association studies wit...

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Autors principals: Fung, Maple M., Rana, Brinda K., Tang, Chih-Min, Shiina, Tetsuo, Nievergelt, Caroline M., Rao, Fangwen, Salem, Rany M., Waalen, Jill, Ziegler, Michael G., Insel, Paul A., O'Connor, Daniel T.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803094/
https://ncbi.nlm.nih.gov/pubmed/19675531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2009.306
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