Φορτώνει......
p53 isoforms, Δ133p53 and p53β, are endogenous regulators of replicative cellular senescence
The finite proliferative potential of normal human cells leads to replicative cellular senescence, which is a critical barrier to tumour progression in vivo1–3. We show that human p53 isoforms (Δ133p53 and p53β)4 constitute an endogenous regulatory mechanism for p53-mediated replicative senescence....
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2802853/ https://ncbi.nlm.nih.gov/pubmed/19701195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1928 |
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