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14-O-Heterocyclic-substituted naltrexone derivatives as non-peptide mu opioid receptor selective antagonists: Design, synthesis, and biological studies

Mu opioid receptor antagonists have clinical utility and are important research tools. To develop non-peptide and highly selective mu opioid receptor antagonist, a series of 14-O-heterocyclic-substituted naltrexone derivatives were designed, synthesized, and evaluated. These compounds showed subnano...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Li, Guo, Aschenbach, Lindsey C. K., He, Hengjun, Selley, Dana E., Zhang, Yan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802822/
https://ncbi.nlm.nih.gov/pubmed/19217280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.12.093
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