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The role of the prion protein membrane anchor in prion infection

Normal cellular and abnormal disease-associated forms of prion protein (PrP) contain a C-terminal glycophosphatidyl-inositol (GPI) membrane anchor. The importance of the GPI membrane anchor in prion diseases is unclear but there are data to suggest that it both is and is not required for abnormal pr...

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Détails bibliographiques
Auteurs principaux: Priola, Suzette A, McNally, Kristin L
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802777/
https://ncbi.nlm.nih.gov/pubmed/19786843
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