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Cells Expressing Anchorless Prion Protein Are Resistant to Scrapie Infection

The hallmark of transmissible spongiform encephalopathies (TSEs or prion diseases) is the accumulation of an abnormally folded, partially protease-resistant form (PrP-res) of the normal protease-sensitive prion protein (PrP-sen). PrP-sen is attached to the cell membrane by a glycosylphosphatidylinos...

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Detalhes bibliográficos
Main Authors: McNally, Kristin L., Ward, Anne E., Priola, Suzette A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668440/
https://ncbi.nlm.nih.gov/pubmed/19225008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02412-08
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