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The role of the prion protein membrane anchor in prion infection

Normal cellular and abnormal disease-associated forms of prion protein (PrP) contain a C-terminal glycophosphatidyl-inositol (GPI) membrane anchor. The importance of the GPI membrane anchor in prion diseases is unclear but there are data to suggest that it both is and is not required for abnormal pr...

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Bibliografske podrobnosti
Main Authors: Priola, Suzette A, McNally, Kristin L
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802777/
https://ncbi.nlm.nih.gov/pubmed/19786843
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