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The cellular prion protein with a monoacylated glycosylphosphatidylinositol anchor modifies cell membranes, inhibits cell signaling and reduces prion formation
The prion diseases occur following the conversion of the cellular prion protein (PrP(C)) into a disease-related isoform (PrP(Sc)). In this study a cell painting technique was used to examine the role of the glycosylphosphatidylinositol (GPI) anchor attached to PrP(C) in prion formation. The introduc...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3166503/ https://ncbi.nlm.nih.gov/pubmed/21738009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.5.2.16095 |
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