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Epigenetics in cancer

Epigenetic mechanisms are essential for normal development and maintenance of tissue-specific gene expression patterns in mammals. Disruption of epigenetic processes can lead to altered gene function and malignant cellular transformation. Global changes in the epigenetic landscape are a hallmark of...

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Autori principali: Sharma, Shikhar, Kelly, Theresa K., Jones, Peter A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802667/
https://ncbi.nlm.nih.gov/pubmed/19752007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp220
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