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At the tipping point for epigenetic therapies in cancer

The field of epigenetics has exploded in the last two decades, with incredible advances in recent years driven by high-throughput sequencing studies. Cancer cells frequently exhibit marked changes in DNA methylation and histone modification during tumorigenesis and tumor progression. These changes i...

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Bibliographic Details
Main Author: Jones, Peter A.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871262/
https://ncbi.nlm.nih.gov/pubmed/24382384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74145
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