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Antagonism of Aryl Hydrocarbon Receptor Signaling by 6,2′,4′-Trimethoxyflavone

The aryl hydrocarbon receptor (AHR) is regarded as an important homeostatic transcriptional regulator within physiological and pathophysiological processes, including xenobiotic metabolism, endocrine function, immunity, and cancer. Agonist activation of the AHR is considered deleterious based on tox...

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Autors principals: Murray, Iain A., Flaveny, Colin A., DiNatale, Brett C., Chairo, Chris R., Schroeder, Jennifer C., Kusnadi, Ann, Perdew, Gary H.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802483/
https://ncbi.nlm.nih.gov/pubmed/19828881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.158261
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