Antagonism of Aryl Hydrocarbon Receptor Signaling by 6,2′,4′-Trimethoxyflavone

The aryl hydrocarbon receptor (AHR) is regarded as an important homeostatic transcriptional regulator within physiological and pathophysiological processes, including xenobiotic metabolism, endocrine function, immunity, and cancer. Agonist activation of the AHR is considered deleterious based on tox...

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Bibliografske podrobnosti
Main Authors: Murray, Iain A., Flaveny, Colin A., DiNatale, Brett C., Chairo, Chris R., Schroeder, Jennifer C., Kusnadi, Ann, Perdew, Gary H.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2010
Teme:
Toxicology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802483/
https://ncbi.nlm.nih.gov/pubmed/19828881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.158261
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