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Development of a Selective Modulator of Aryl Hydrocarbon (Ah) Receptor Activity that Exhibits Anti-Inflammatory Properties

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that mediates the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin. However, the role of the AHR in normal physiology is still an area of intense investigation. For example, this receptor plays an important role in certain...

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Detalhes bibliográficos
Main Authors: Murray, Iain A., Krishnegowda, Gowdahalli, DiNatale, Brett C., Flaveny, Colin, Chiaro, Chris, Lin, Jyh-Ming, Sharma, Arun K., Amin, Shantu, Perdew, Gary H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871980/
https://ncbi.nlm.nih.gov/pubmed/20423157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx100045h
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