Molecular cloning of L-methylmalonyl-CoA mutase: gene transfer and analysis of mut cell lines.

L-Methylmalonyl-CoA mutase (MCM, EC 5.4.99.2) is a mitochondrial adenosylcobalamin-requiring enzyme that catalyzes the isomerization of L-methylmalonyl-CoA to succinyl-CoA. This enzyme is deficient in methylmalonic acidemia, an often fatal disorder of organic acid metabolism. Antibody against human...

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Detaylı Bibliyografya
Asıl Yazarlar: Ledley, F D, Lumetta, M, Nguyen, P N, Kolhouse, J F, Allen, R H
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1988
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC280243/
https://ncbi.nlm.nih.gov/pubmed/2453061
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