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Heterogeneous alleles and expression of methylmalonyl CoA mutase in mut methylmalonic acidemia.

Methylmalonic acidemia (MMA) can be caused by mutations in the gene coding for the methylmalonyl CoA mutase (MCM) apoenzyme or by mutations in genes required for provision of its adenosylcobalamin cofactor. We have characterized MCM activity, gene structure, and expression in a series of primary fib...

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Detalhes bibliográficos
Main Authors: Ledley, F D, Crane, A M, Lumetta, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1683614/
https://ncbi.nlm.nih.gov/pubmed/1968706
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