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Studies on the Effect of Water-Soluble Polymers on Drug–Cyclodextrin Complex Solubility
The effect of complexation of irbesartan (IRB), a practically water-insoluble drug, with cyclodextrins in presence of different concentrations of water-soluble polymers (PEG 4000 and PVP K-90) on the dissolution rate of the drug has been investigated. Phase solubility studies were carried out to eva...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Springer US
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2802171/ https://ncbi.nlm.nih.gov/pubmed/19562489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9274-6 |
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