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Effect of Cyclodextrin Types and Co-Solvent on Solubility of a Poorly Water Soluble Drug

The aim of the study was to investigate the solubility of piroxicam (Prx) depending on the inclusion complexation with various cyclodextrins (CDs) and on ethanol as a co-solvent. The phase-solubility method was applied to determine drug solubility in binary and ternary systems. The results showed th...

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Bibliografiske detaljer
Udgivet i:Sci Pharm
Main Authors: Charumanee, Suporn, Okonogi, Siriporn, Sirithunyalug, Jakkapan, Wolschann, Peter, Viernstein, Helmut
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198028/
https://ncbi.nlm.nih.gov/pubmed/27763573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/scipharm84040694
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