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Multicomponent cyclodextrin system for improvement of solubility and dissolution rate of poorly water soluble drug()

The purpose of the present study was to investigate the interaction of Cinnarizine (CIN) with Hydroxypropyl-β-Cyclodextrin (HPβCD) in the presence of Hydroxy Acids (HA). Various binary and ternary systems of CIN with HPβCD and HA were prepared by kneading and coevaporation methods. For the ternary s...

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Publicat a:Asian J Pharm Sci
Autors principals: Patel, Mayank, Hirlekar, Rajashree
Format: Artigo
Idioma:Inglês
Publicat: Shenyang Pharmaceutical University 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032147/
https://ncbi.nlm.nih.gov/pubmed/32104443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2018.02.007
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