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Multicomponent cyclodextrin system for improvement of solubility and dissolution rate of poorly water soluble drug()

The purpose of the present study was to investigate the interaction of Cinnarizine (CIN) with Hydroxypropyl-β-Cyclodextrin (HPβCD) in the presence of Hydroxy Acids (HA). Various binary and ternary systems of CIN with HPβCD and HA were prepared by kneading and coevaporation methods. For the ternary s...

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Detalhes bibliográficos
Publicado no:Asian J Pharm Sci
Main Authors: Patel, Mayank, Hirlekar, Rajashree
Formato: Artigo
Idioma:Inglês
Publicado em: Shenyang Pharmaceutical University 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032147/
https://ncbi.nlm.nih.gov/pubmed/32104443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2018.02.007
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