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Improvement of Dissolution Behavior for Poorly Water-Soluble Drug by Application of Cyclodextrin in Extrusion Process: Comparison between Melt Extrusion and Wet Extrusion

The purpose of this study was to improve dissolution behavior of poorly water-soluble drugs by application of cyclodextrin in extrusion processes, which were melt extrusion process and wet extrusion process. Indomethacin (IM) was employed as a model drug. Extrudates containing IM and 2-hydroxypropyl...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Yano, Hideki, Kleinebudde, Peter
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Springer US 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902314/
https://ncbi.nlm.nih.gov/pubmed/20496019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9448-2
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