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Preformulation Study of the Inclusion Complex Irbesartan-β-Cyclodextrin
The aim of the present work was to improve the solubility and dissolution profile of Irbesartan (IRB), a poorly water-soluble drug by formation of inclusion complex with β-cyclodextrin (βCD). Phase solubility studies revealed increase in solubility of the drug upon cyclodextrin addition, showing A(L...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2663696/ https://ncbi.nlm.nih.gov/pubmed/19283492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9206-5 |
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