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Molecular Inclusion Complexes of β-Cyclodextrin Derivatives Enhance Aqueous Solubility and Cellular Internalization of Paclitaxel: Preformulation and In vitro Assessments

Drugs with low aqueous solubility and permeability possess substantial challenges in designing effective and safe formulations. Synergistic solubility and permeability enhancement in a simple formulation can increase bioavailability and efficacy of such drugs. To overcome limitations of the clinical...

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Detalhes bibliográficos
Publicado no:J Pharm Pharmacol (Los Angel)
Main Authors: Shah, Milin, Shah, Vatsal, Ghosh, Anasuya, Zhang, Zheng, Minko, Tamara
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418459/
https://ncbi.nlm.nih.gov/pubmed/25950011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.13188/2327-204X.1000011
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