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Lessons from Lactose Permease

An X-ray structure of the lactose permease of Escherichia coli (LacY) in an inward-facing conformation has been solved. LacY contains N- and C-terminal domains, each with six transmembrane helices, positioned pseudosymmetrically. Ligand is bound at the apex of a hydrophilic cavity in the approximate...

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Dettagli Bibliografici
Autori principali: Guan, Lan, Kaback, H. Ronald
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802108/
https://ncbi.nlm.nih.gov/pubmed/16689628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.biophys.35.040405.102005
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