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Hyperglycemia Alters the Schwann Cell Mitochondrial Proteome and Decreases Coupled Respiration in the Absence of Superoxide Production

Hyperglycemia-induced mitochondrial dysfunction contributes to sensory neuron pathology in diabetic neuropathy. Although Schwann cells (SCs) also undergo substantial degeneration in diabetic neuropathy, the effect of hyperglycemia on SC mitochondrial proteome and mitochondrial function has not been...

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Detalhes bibliográficos
Main Authors: Zhang, Liang, Yu, Cuijuan, Vasquez, Francisco E., Galeva, Nadya, Onyango, Isaac, Swerdlow, Russell H., Dobrowsky, Rick T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801777/
https://ncbi.nlm.nih.gov/pubmed/19905032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr900818g
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