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Hyperglycemia and Downregulation of Caveolin-1 Enhance Neuregulin-Induced Demyelination

Neuregulins (NRGs) are growth factors which bind to Erb receptor tyrosine kinases that localize to Schwann cells (SCs). Although NRGs can promote cell survival, mitogenesis, and myelination in undifferentiated SCs, they also induce demyelination of myelinated co-cultures of SCs and dorsal root gangl...

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Bibliografische gegevens
Hoofdauteurs: YU, CUIJUAN, ROUEN, SHEFALI, DOBROWSKY, RICK T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553896/
https://ncbi.nlm.nih.gov/pubmed/18338795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20662
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