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Hyperglycemia and Downregulation of Caveolin-1 Enhance Neuregulin-Induced Demyelination
Neuregulins (NRGs) are growth factors which bind to Erb receptor tyrosine kinases that localize to Schwann cells (SCs). Although NRGs can promote cell survival, mitogenesis, and myelination in undifferentiated SCs, they also induce demyelination of myelinated co-cultures of SCs and dorsal root gangl...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2553896/ https://ncbi.nlm.nih.gov/pubmed/18338795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20662 |
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