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The Anti-Helminthic Niclosamide Inhibits Wnt/Frizzled1 Signaling
Wnt proteins bind to seven-transmembrane Frizzled receptors to mediate the important developmental, morphogenetic, and tissue-regenerative effects of Wnt signaling. Dysregulated Wnt signaling is associated with many cancers. Currently there exist no drug candidates, or even tool compounds that modul...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2801776/ https://ncbi.nlm.nih.gov/pubmed/19772353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9009677 |
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