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INTERACTIONS OF HUMAN O(6)-ALKYLGUANINE-DNA ALKYLTRANSFERASE (AGT) WITH SHORT DOUBLE-STRANDED DNAS

O(6)-alkylguanine-DNA alkyltransferase (AGT) is a ubiquitous enzyme with an amino acid sequence that is conserved in Eubacteria, Archaea and Eukarya. It repairs O(6)-alkylguanine and O(4)-alkylthymine adducts in single-stranded and duplex DNAs. In performing these functions, AGT must partition betwe...

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Bibliografske podrobnosti
Main Authors: Melikishvili, Manana, Rasimas, Joseph J., Pegg, Anthony E., Fried, Michael G.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801566/
https://ncbi.nlm.nih.gov/pubmed/19061338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801666c
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