Glinide, but Not Sulfonylurea, Can Evoke Insulin Exocytosis by Repetitive Stimulation: Imaging Analysis of Insulin Exocytosis by Secretagogue-Induced Repetitive Stimulations

To investigate the different effects between sulfonylurea (SU) and glinide drugs in insulin secretion, pancreatic β-cells were repeatedly stimulated with SU (glimepiride) or glinide (mitiglinide). Total internal reflection fluorescent (TIRF) microscopy revealed that secondary stimulation with glimep...

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Detalhes bibliográficos
Main Authors: Aoyagi, Kyota, Ohara-Imaizumi, Mica, Nishiwaki, Chiyono, Nakamichi, Yoko, Nagamatsu, Shinya
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801449/
https://ncbi.nlm.nih.gov/pubmed/20069052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/278762
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