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Disruption of the Axon Initial Segment Cytoskeleton Is a New Mechanism for Neuronal Injury
Many factors contribute to nervous system dysfunction and failure to regenerate after injury or disease. Here, we describe a previously unrecognized mechanism for nervous system injury. We show that neuronal injury causes rapid, irreversible, and preferential proteolysis of the axon initial segment...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for Neuroscience
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2801423/ https://ncbi.nlm.nih.gov/pubmed/19846712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3376-09.2009 |
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