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Axon Initial Segment Cytoskeleton: Architecture, Development, and Role in Neuron Polarity

The axon initial segment (AIS) is a specialized structure in neurons that resides in between axonal and somatodendritic domains. The localization of the AIS in neurons is ideal for its two major functions: it serves as the site of action potential firing and helps to maintain neuron polarity. It has...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neural Plast
Hauptverfasser: Jones, Steven L., Svitkina, Tatyana M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967436/
https://ncbi.nlm.nih.gov/pubmed/27493806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/6808293
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