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Axon Initial Segment Cytoskeleton: Architecture, Development, and Role in Neuron Polarity

The axon initial segment (AIS) is a specialized structure in neurons that resides in between axonal and somatodendritic domains. The localization of the AIS in neurons is ideal for its two major functions: it serves as the site of action potential firing and helps to maintain neuron polarity. It has...

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Bibliografiske detaljer
Main Authors: Steven L. Jones, Tatyana M. Svitkina
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2016-01-01
Serier:Neural Plasticity
Online adgang:http://dx.doi.org/10.1155/2016/6808293
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