Calcineurin Signaling Mediates Disruption of the Axon Initial Segment Cytoskeleton after Injury

The axon initial segment (AIS) cytoskeleton undergoes rapid and irreversible disruption prior to cell death after injury, and loss of AIS integrity can produce profound neurological effects on the nervous system. Here we described a previously unrecognized mechanism for ischemia-induced alterations...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:iScience
Main Authors: Zhao, Yanan, Wu, Xuanyuan, Chen, Xin, Li, Jianan, Tian, Cuiping, Chen, Jiangrui, Xiao, Cheng, Zhong, Guisheng, He, Shuijin
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031317/
https://ncbi.nlm.nih.gov/pubmed/32062456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.100880
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