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Cre Recombination Mediated Cassette Exchange For Building Versatile Transgenic Human ESC lines
To circumvent the silencing effect of transgene expression in human embryonic stem cells (hESC), we employed the Cre recombination mediated cassette exchange strategy to target the silencing-resistant site in the genome. We have identified new loci that sustain transgene expression during stem cell...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2801346/ https://ncbi.nlm.nih.gov/pubmed/19415769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.38 |
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