In Vivo Stoichiometry of Shelterin Components

Human telomeres bind shelterin, the six-subunit protein complex that protects chromosome ends from the DNA damage response and regulates telomere length maintenance by telomerase. We used quantitative immunoblotting to determine the abundance and stoichiometry of the shelterin proteins in the chroma...

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Bibliografiske detaljer
Main Authors: Takai, Kaori K., Hooper, Sarah, Blackwood, Stephanie, Gandhi, Rita, de Lange, Titia
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801271/
https://ncbi.nlm.nih.gov/pubmed/19864690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.038026
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