In Vivo Stoichiometry of Shelterin Components

Human telomeres bind shelterin, the six-subunit protein complex that protects chromosome ends from the DNA damage response and regulates telomere length maintenance by telomerase. We used quantitative immunoblotting to determine the abundance and stoichiometry of the shelterin proteins in the chroma...

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Bibliographic Details
Main Authors: Takai, Kaori K., Hooper, Sarah, Blackwood, Stephanie, Gandhi, Rita, de Lange, Titia
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801271/
https://ncbi.nlm.nih.gov/pubmed/19864690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.038026
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