In Vivo Stoichiometry of Shelterin Components

Human telomeres bind shelterin, the six-subunit protein complex that protects chromosome ends from the DNA damage response and regulates telomere length maintenance by telomerase. We used quantitative immunoblotting to determine the abundance and stoichiometry of the shelterin proteins in the chroma...

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Autors principals: Takai, Kaori K., Hooper, Sarah, Blackwood, Stephanie, Gandhi, Rita, de Lange, Titia
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
Matèries:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801271/
https://ncbi.nlm.nih.gov/pubmed/19864690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.038026
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