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The Shelterin Component TPP1 Is a Binding Partner and Substrate for the Deubiquitinating Enzyme USP7

The telomeric shelterin component TPP1 has critical functions in telomeric protein complex assembly and telomerase recruitment and regulation. Here we identify USP7 as a novel interacting protein of the oligonucleotide/oligosaccharide-binding fold of TPP1, which was previously known to recruit telom...

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Bibliografiska uppgifter
Huvudupphovsmän: Zemp, Ivo, Lingner, Joachim
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192509/
https://ncbi.nlm.nih.gov/pubmed/25172512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.596056
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