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Decreased Superoxide Production in Macrophages of Long-lived p66Shc Knock-out Mice
A decrease in reactive oxygen species (ROS) production has been associated with extended life span in animal models of longevity. Mice deficient in the p66Shc gene are long-lived, and their cells are both resistant to oxidative stress and produce less ROS. Our microarray analysis of p66Shc(−/−) mous...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2801244/ https://ncbi.nlm.nih.gov/pubmed/19892704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.017491 |
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